Transplant the hoodia plant to a pot filled with succulent and cactus potting medium if it is a hoodia cutlet. Although hoodias grown from seed can thrive in any type of soil, cutlets perform best in soil that mimics their native environment. The pot should have plenty of drainage holes to prevent root rot.
Water the hoodia sparingly once every three months. If your region is particularly humid, watering may be necessary only once every four months. Seedlings require a little more water, however. Water seedlings twice weekly until the plant becomes established. Do not water hoodias in weather of 95 degrees Fahrenheit or above. Watering is the trickiest part of hoodia care, since over-watering will quickly kill the plant.
Put the hoodia in a well-lighted area. Although hoodia plants do not require direct sun, they do need lots of light to perform optimally. Hoodia plants become dormant in cold weather, so consider keeping them indoors or in a temperature-controlled greenhouse in the winter months.