Grow "Epiphyllum oxypetalum" in well-aerated potting mix. Buy or prepare your own blend by mixing 1 part small pine bark, 1 part coarse sand and 2 parts peat moss.
Water the cactus as often as it takes to maintain moist soil. Irrigate the potting mix until water flows out of the pot's drainage holes. Maintain hydrated roots year-round.
Feed "Epiphyllum oxypetalum" a fertilizer that contains equal amounts of nitrogen, phosphorous and potassium, such as a 10-10-10 analysis. Dilute the nutrient to 1/2 the strength recommended on the manufacturer's label. Water the plant with this solution once a month. Do not fertilize this cactus in the winter.
Slide the plant out of its pot every two years. Discard the old soil and wash the planter. Repot the cactus in a fresh batch of potting mix. Water thoroughly.