Remove the fish and drain the water from the glass fish tank. Make sure the tank is dry before you begin to repair it.
Move the fish tank to a well-ventilated area. Silicone gives off a rather strong odor when it is drying,so perform this task away from the living area of your house.
Determine the location of the leak. If it's coming from the bottom seam, remove the trim to access to the seam.
Use a razor blade to cut away the seam of silicone where the leak is located. To prevent cutting yourself with the razor blade, you may wish to use a vise grip or regular pair of pliers to hold the razor while making the cut.
Wipe the area of the repair with white vinegar to clean it.
Run a bead of silicone along the area you are repairing. Wet your finger with water and run it along the bead line to smooth it out.