Walk to the main fuse box for the home and turn off power for the heating or cooling system that the vents are attached to. This prevents the system from coming on and blowing dust particles into your eyes during the removal process.
Go to the room where you want to remove the ceiling vent. Place a stepladder under the vent and climb onto it carrying a screwdriver.
Locate the screws in the outer faceplate of the ceiling vent. Most rectangular vents have a screw on either side. On circular vents, the screw is typically located in the center of the faceplate.
Place one hand over the vent in case it falls when you remove the screws. Insert the screwdriver into the screws and turn them counterclockwise until they come out of the vent. Place the screws in your pocket as you remove them so that you do not lose them.
Grasp the edge of the ceiling vent with your hands and pull it straight down out of the ceiling. If you have a hard time grasping it, insert a flat head screwdriver under one edge to help pry it out of ceiling.